Raquel Jiménez‐Herrera

This study shows that activating sigma-1 receptors with PRE-084 rescues synaptic plasticity and memory impairments caused by amyloid-beta oligomers in an Alzheimer's disease model.

The paper tests a GIRK channel activator in AD models, finding low doses improve synaptic plasticity and memory without sex differences, while high doses impair function in healthy mice.

The paper maps spatial proteomic changes in dorsal and ventral hippocampus of male and female Alzheimer's disease models, identifying sex-dependent protein alterations linked to synaptic plasticity and GSK-3β activity.

This study characterizes the effects of Aβ1-42 injection on memory and synaptic plasticity in male and female mice, finding long-lasting impairments in both sexes.