Junjie Xia

Spatial proximity sequencing maps developmental dynamics in the germinal center

This paper introduces Sprox-seq, a multi-omic technique that maps protein interactions and mRNA in human germinal centers, revealing distinct B cell maturation pathways and spatially-enriched immune regulatory complexes.

Accurate processing of ultra-short immune signals by singlemacrophages

This study shows single macrophages can accurately detect and respond to short-lived immune signals through receptor cooperativity and pathway variability.

Computational prediction of protein interactions on single cells by proximity sequencing

The paper introduces a physical model and improved analysis methods for quantifying protein complexes from Prox-seq data, enhancing accuracy and robustness.