Author

Qirui Deng

Sun Yat-sen UniversityORCID 0009-0004-3750-4330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Jinping LeiiD· 2 shared Mingyuan XuiD· 2 shared Anjie QiaoiD· 1 shared Chang‐Yu HsiehiD· 1 shared Chaoming Huang· 1 shared Chen Hong-mingiD· 1 shared Hao ZhangiD· 1 shared Hongming CheniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Jinping LeiORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 11, 2026

PeTFlow: Flow-Matching Based All-Atom Peptide Design through Side-Chain State Tokenization

Qirui Deng, Mingyuan Xu, Chen Hong-ming, Jinping Lei

PeTFlow designs peptides by optimizing sequence, conformation, and side-chain packing using flow-matching and state tokenization, achieving high-quality results on benchmarks.

DOI 10.64898/2026.10.09.757799

protein structuredeep learning

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BioinformaticsJACS AuPeer-reviewedJul 7, 2026

SynPROTAC: synthesizable PROTACs design through synthesis constrained generative model and reinforcement learning

Mingyuan Xu, Chaoming Huang, Li Pang…·Jinping Lei

SynPROTAC generates novel PROTAC molecules with feasible synthetic routes and favorable properties using a synthesis-constrained generative model and reinforcement learning.

DOI 10.1021/jacsau.6c00732

deep learningtransformer / foundation model

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