Author

Mihai Simioniuc

University of GroningenORCID 0009-0004-4206-0690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Danny IncarnatoiD· 1 shared Frans BianchiiD· 1 shared Geert van den BogaartiD· 1 shared Hjalmar R. BoumaiD· 1 shared Lisanne Boekhoud· 1 shared Martijn den Ouden· 1 shared Melina IoannidisiD· 1 shared Pieter Grijpstra· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Danny IncarnatoORCID

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1 paper

Recent·Most cited

4-Hydroxynonenal suppresses IL-10 production during infection

Melina Ioannidis, Sjors Maassen, Lisanne Boekhoud, Martijn den Ouden, Mihai Simioniuc, Pieter Grijpstra, Danny Incarnato, Frans Bianchi, Hjalmar R. Bouma, Geert van den Bogaart

This study shows that 4-HNE suppresses IL-10 production in sepsis while leaving IL-6 and TNF- unaffected, through mechanisms involving HIF-1 and NF-κB signaling.

bioRxiv · Nov 24, 2025 · PreprintImmunology