ImmunologybioRxivPreprint
4-Hydroxynonenal suppresses IL-10 production during infection
Melina Ioannidis, Sjors Maassen, Lisanne Boekhoud…·Geert van den Bogaart
This study shows that 4-HNE suppresses IL-10 production in sepsis while leaving IL-6 and TNF- unaffected, through mechanisms involving HIF-1 and NF-κB signaling.
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