MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewed
Discovery and Characterization of a Hydroxypyridone-3-carboxamide Analog as an Antiviral Lead against Orthopoxviruses
Anil Pant, Ajit Dhananjay Jagtap, Jiashu Xie…·Zhilong Yang
This study identifies ZW-2038, a hydroxypyridone-3-carboxamide analog, as an antiviral lead against orthopoxviruses with low micromolar potency and selectivity in human fibroblasts and organoid models.