Author

Lara Dsouza

Texas A&M UniversityORCID 0000-0002-0769-0177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Anil PantiD· 3 shared Zhilong YangiD· 3 shared Djamal Brahim BelhaouariiD· 2 shared Zhengqiang WangiD· 2 shared Ahmad AliiD· 1 shared Ajit Dhananjay JagtapiD· 1 shared Bentley Chai· 1 shared Blake PopeiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Anil PantORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Course-Undergraduate Research Experience (CURE) to explore the effect of structural variants on gene expression in C. elegans balancers

Tatiana Maroilley, Victoria Rodrigues Alves Barbosa, Rumika Mascarenhas, Suzanne Ferris, Catherine T.M. Diao, Fatemah AlAwadhi, Saood Aldakheel, Ahmad Ali, Denah Alkanderi, Meshary Alshatti, Samyah Alsuwaileh, Ryan Bui, Bentley Chai, Lara Dsouza, Parisa Etemadi Nezhad, , Maja Tarailo‐Graovac

Students investigated structural variants' effects on gene expression in C. elegans balancers using bioinformatics tools and reported molecular mechanisms and unexpected gene expression effects.

PLoS ONE · Aug 11, 2026Peer-reviewedBioinformatics

Discovery and Characterization of a Hydroxypyridone-3-carboxamide Analog as an Antiviral Lead against Orthopoxviruses

Anil Pant, Ajit Dhananjay Jagtap, Jiashu Xie, Djamal Brahim Belhaouari, Wei Xie, Jacob P. Mahoney, Lara Dsouza, Ziyue Wang, Zeinab R. Aboezz, Tibor Farkas, Zhengqiang Wang, Zhilong Yang

This study identifies ZW-2038, a hydroxypyridone-3-carboxamide analog, as an antiviral lead against orthopoxviruses with low micromolar potency and selectivity in human fibroblasts and organoid models.

Antimicrobial Agents and Chemotherapy · Jun 18, 2026Peer-reviewedMicrobiology

Ciclopirox suppresses poxvirus replication by targeting iron metabolism

Anil Pant, Djamal Brahim Belhaouari, Lara Dsouza, D.M. Nirosh Udayanga, Zhengqiang Wang, Zhilong Yang

This study identifies ciclopirox as an antiviral agent that suppresses poxvirus replication by targeting host iron metabolism.

Antiviral Research · Oct 9, 2025Peer-reviewedMicrobiology

Role of vaccinia virus growth factor in stimulating the mTORC1-CAD axis of the de novo pyrimidine pathway under different nutritional cues

Lara Dsouza, Anil Pant, Blake Pope, Zhilong Yang

This study identifies vaccinia virus growth factor (VGF) as a key factor enabling mTORC1-CAD axis activation in nutrient-poor conditions, enhancing de novo pyrimidine synthesis for viral replication.

Journal of Virology · Jan 16, 2025Peer-reviewedMicrobiology