Pharmacology & ToxicologyArchives of ToxicologyPeer-reviewed
Systematic assessment of transcriptomic and phenotypic biological profiling for mechanism-based hazard assessment using target-annotated reference chemicals in renal proximal tubular epithelial cells
Hugo W van Kessel, Marlene Wedler, Palle Steen Helmke…·Bob van de Water
This study evaluates transcriptomic and morphological profiling methods for hazard assessment using reference chemicals in renal cells, finding HTTr provides higher mechanistic resolution than CPP.
DOI 10.1007/s00204-026-04612-8