Anastasiia Dudkovskaia

Fetal signatures in the 3D genome of iPSC-derived neurons and their implications for disease modeling

This study compares chromatin architecture in iPSC-derived neurons to fetal and mature neurons, finding iPSC-derived neurons resemble fetal neurons and have distinct chromatin features.

Accelerated Aging Signatures in 3D Genome Organization and Transcriptome in Schizophrenia

This study identifies accelerated aging patterns in 3D genome organization and transcriptome in schizophrenia using Hi-C data and transcriptomic analysis.

ComputAgeBench: Epigenetic Aging Clocks Benchmark

ComputAgeBench benchmarks epigenetic aging clocks by comparing 13 models on 66 harmonized blood DNA methylation datasets to evaluate their ability to distinguish healthy individuals from those with aging-accelerating conditions.