Sergey V. Razin

This study compares chromatin architecture in iPSC-derived neurons to fetal and mature neurons, finding iPSC-derived neurons resemble fetal neurons and have distinct chromatin features.

This study identifies interchromosomal interactions between chr19 and the CCND1 locus in MCL, linking spatial genome reorganization to disease-specific transcriptional programs.

This study identifies accelerated aging patterns in 3D genome organization and transcriptome in schizophrenia using Hi-C data and transcriptomic analysis.

The paper identifies 'fountains' as enhancer-specific chromosome organization elements emerging during zygotic genome activation in zebrafish and mouse.

The paper investigates how Polycomb proteins regulate gene expression in human cortical neurons through long-range chromatin interactions, showing their role in cell-type specification.

This study identifies long non-coding RNAs (lncRNAs) as guides for the SWI/SNF complex to cell-specific enhancers, revealing a mechanism for chromatin accessibility and gene expression control.

This study introduces MChIP-C, a method to measure chromatin interactions at single-nucleosome resolution, and supports the enhancer-promoter looping model using data from K562 cells and CRISPRi screens.

The paper identifies Elys as a nucleoporin linking peripheral chromatin to nuclear pores in interphase nuclei and shows its role in chromatin organization and gene regulation.

The paper investigates chromatin looping in Dictyostelium discoideum, finding that convergent gene pairs act as directional barriers for chromatin extrusion during development.

The paper maps 3D genome architecture in neuronal and non-neuronal cells, finding reduced compartmentalization and increased long-range polycomb interactions in neurons.

This study uses 3C-seq to analyze the chromosome conformation of Thermofilum adornatum, revealing a curved secondary diagonal and A/B compartments without observed loops or plaid patterns.

The paper investigates how 1,6-hexanediol modulates liquid-liquid phase separation and its impact on 3D chromatin organization in living cells.

The paper introduces Red-C, a method to study RNA-DNA interactions, identifies ncRNAs associated with repressed chromatin, and traces mRNA production kinetics in K562 cells.