Isabelle Loïodice

This paper shows that the fungal ATRX ortholog SAD-6 uses a unique histone H4 variant for genome surveillance and defense, revealing its role in various genomic regions and a repeat-induced point mutation pathway.

The paper identifies Esc1-mediated telomere anchoring as a mechanism regulating telomere clustering in yeast during metabolic shifts to quiescence.

The paper shows that perturbed chromatin in Neurospora crassa can trigger de novo transcriptional and post-transcriptional silencing, mediated by SAD-6, a chromatin remodeler.