Eugene A. Gladyshev

SAD-6/ATRX enables broad genome surveillance and defense in fungi

This paper shows that the fungal ATRX ortholog SAD-6 uses a unique histone H4 variant for genome surveillance and defense, revealing its role in various genomic regions and a repeat-induced point mutation pathway.

Properties of DNA in concentrated aqueous solutions of LiCl suggest transition to C-DNA

The paper investigates the B-to-C DNA transition in aqueous LiCl solutions and finds increased helical twist across all tested concentrations, suggesting C-DNA stability above 8 M LiCl.

Remodeling of perturbed chromatin can initiate de novo transcriptional and post-transcriptional silencing

The paper shows that perturbed chromatin in Neurospora crassa can trigger de novo transcriptional and post-transcriptional silencing, mediated by SAD-6, a chromatin remodeler.

Regulation of DIM-2-dependent repeat-induced point mutation (RIP) by the recombination-independent homologous DNA pairing in Neurospora crassa

The paper investigates DIM-2-dependent RIP in Neurospora crassa, showing GC-rich repeats and direct repeats enhance RIP efficiency through homologous DNA pairing and quadruplex formation.

Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa

The paper demonstrates a recombination-independent mechanism for DNA homology recognition in meiosis using Neurospora crassa, showing that homologous DNA pairs through specific sequence patterns and structural interactions.

DNA sequence homology induces cytosine-to-thymine mutation by a heterochromatin-related pathway

The paper shows that DNA sequence homology can induce cytosine-to-thymine mutations via a heterochromatin-related pathway in Neurospora crassa.