ImmunologybioRxivPreprint
Deep mapping of the TCR-antigen interface using pMHC-pseudotyped viruses and yeast display
Stephanie A. Gaglione, Jonathan Krog, Frances R Keer…·Michael E. Birnbaum
The paper introduces VelociRAPTR, a method to map TCR-antigen interactions by combining yeast-displayed TCR libraries with pMHC-displaying virus-like particles, revealing biased recognition patterns and enabling TCR engineering.
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