Small GTPases RhoA and RhoC coordinately regulate cardiomyocyte size in the mouse heart
Vikram Prasad, Naga Swathi Sree Kavuri, Max Toubin, J. Matthew Kofron, Yi Zheng, Jop H. van Berlo, Jeffery D. Molkentin, Davy Vanhoutte
This study shows RhoA and RhoC regulate cardiomyocyte size and cardiac remodeling, with compensatory effects and stress-dependent contributions to hypertrophy and function.
bioRxiv · Oct 14, 2026 · PreprintCell Biology