Outcome-Driven Microscopy: Closed-Loop Optogenetic Control of Cell Biology
Josiah B. Passmore, Alfredo Rates, Jakob Schröder, Menno T. P. van Laarhoven, Vincent J. W. Hellebrekers, Henrik G. van Hoef, Antonius J. M. Geurts, Wendy van Straaten, Wilco Nijenhuis, Florian Berger, Carlas Smith, Ihor Smal, Lukas C. Kapitein
This paper introduces outcome-driven microscopy, combining optogenetics and smart microscopy to achieve precise control over cellular behavior through predefined outcomes.
Nature Communications · Dec 23, 2025Peer-reviewedCell Biology