GeneticsbioRxivPreprint
Loss of Bbs8 leads to cystic kidney disease in mice with reduced acetylation of ciliary alpha-tubulin through HDAC2
Emilia Kieckhöfer, Julia Günzler, Peter Andreas Matthiessen…·Bernhard Schermer
This study shows that loss of Bbs8 in mice causes cystic kidney disease by reducing ciliary alpha-tubulin acetylation through increased HDAC2 activity.
DOI 10.1101/2024.03.07.583949