Author

Thomas Beck Lindhardt

Aarhus UniversityORCID 0009-0004-7977-3141Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

Brian HanseniD· 2 shared Christian Stald SkoveniD· 2 shared Leif ØstergaardiD· 2 shared Aleksandar J. KrmpotiD· 1 shared Boris Wied· 1 shared Dmitry D. PostnoviD· 1 shared Eugenio Gutiérrez‐JiméneziD· 1 shared Filip Mrotek· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Brian HansenORCID

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2 papers

Recent·Most cited

Sex shapes capillary flows and oxygen extraction in the middle-aged mouse brain

Eugenio Gutiérrez‐Jiménez, Boris Wied, Thomas Beck Lindhardt, Signe H. Mikkelsen, Rasmus West Knopper, Christian Stald Skoven, Oliver Bundgaard Christensen, Vitalii Dashkovskyi, Filip Mrotek, Peter Mondrup Rasmussen, Maria Hovmann Andresen, Aleksandar J. Krmpot, Mirna El Khatib, Sergei A. Vinogradov, Sava Sakadžić, , Leif Østergaard

The paper shows that female mice have higher cortical blood flow and reduced oxygen extraction fraction in middle age, with molecular and structural differences in white matter and microglial reactivity, without differences in systemic markers.

bioRxiv · Oct 18, 2026 · PreprintNeuroscience

Anesthesia-related brain microstructure modulations detected by diffusion MRI

Thomas Beck Lindhardt, Christian Stald Skoven, Luca Bordoni, Leif Østergaard, Zhifeng Liang, Brian Hansen

This study uses diffusion kurtosis MRI to show that anesthesia reduces mean diffusivity and kurtosis in both gray and white matter of mice, suggesting increased extracellular space volume.

NMR in Biomedicine · Sep 15, 2023Peer-reviewedNeuroscience