Eamon M. McAndrew

Imaging-based spatial isoform transcriptomics resolves transcript diversity at cellular and subcellular resolution

The paper introduces iSiT, an imaging-based spatial isoform transcriptomics method, and demonstrates its application in the mouse brain to study transcript isoform diversity at cellular and subcellular resolution.

Allos: an integrated Python toolkit for isoform-level single-cell and spatial in-situ transcriptomics

Allos provides a Python framework for isoform-level analysis of single-cell and spatial transcriptomics data, integrating with existing tools and enabling differential isoform usage screening and visualization.

Cell culture differentiation and proliferation conditions influence the in vitro regeneration of the human airway epithelium

This study evaluates how different culture media affect the differentiation and proliferation of human airway epithelial cells in vitro using single-cell RNA sequencing and imaging.