Author

Aitana de la Cuadra Basté

University of DundeeORCID 0009-0004-9112-2747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1

Frequent Co-Authors

Alessio CiulliiD· 1 shared Carlo J. A. VerhoefiD· 1 shared Charlotte CroweiD· 1 shared Christian OttmanniD· 1 shared Gajanan J. SatheiD· 1 shared Kentaro IsoiD· 1 shared Luc BrunsveldiD· 1 shared Mark A. NakasoneiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alessio CiulliORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintNov 17, 2025

Induced ubiquitination of the partially disordered Estrogen Receptor alpha protein via a 14-3-3-directed molecular glue-based PROTAC design

Carlo J. A. Verhoef, Charlotte Crowe, Mark A. Nakasone…·Peter J. Cossar

This paper develops a molecular glue-based PROTAC (MGPROTACs) to ubiquitinate the 14-3-3/Estrogen Receptor complex, demonstrating cooperative complex formation and selective ubiquitination through linker design.

DOI 10.1101/2025.11.17.688825

protein structuredeep learning

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