Author

Aurelija L Ippolito

University of Oxford;ORCID 0009-0004-9219-6502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Antony GalioneiD· 1 shared Gary GilmouriD· 1 shared Grant Charles ChurchilliD· 1 shared Trevor SharpiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperPharmacology & Toxicology

Antony GalioneORCID

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1 paper

Recent·Most cited

A novel 5-HT2A receptor-linked signalling pathway involving NAADP-mediated lysosomal Ca2+ release

Aurelija L Ippolito, Antony Galione, Gary Gilmour, Grant Charles Churchill, Trevor Sharp

This paper discovers a novel 5-HT2A receptor-linked signaling pathway involving NAADP-mediated lysosomal Ca2+ release, showing reduced hallucinogenic and neuroplastic effects upon genetic ablation of the pathway in mice.

bioRxiv · Nov 3, 2026 · PreprintPharmacology & Toxicology