Author

Sabina Sarvan

University of OttawaORCID 0009-0004-9702-956XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jean‐François CoutureiD· 2 shared Alejandro Saettone· 1 shared Angelica Venes· 1 shared Anne‐Claude GingrasiD· 1 shared Ayala Milo· 1 shared Carol Chen· 1 shared Cassandra J. WongiD· 1 shared Elizabeth J. K. BhojiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Jean‐François CoutureORCID

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2 papers

Recent·Most cited

H3.3 De Novo Mutations Alter Lysine 36 Methylation via Distinct Mechanisms

Shahir M. Morcos, Sabina Sarvan, Alejandro Saettone, Cassandra J. Wong, Scott Vo, Ayala Milo, Omar H. Bayoumy, Rajesh Angireddy, Giovanni L. Burke, Jack Greenblatt, Nada Jabado, Carol Chen, Elizabeth J. K. Bhoj, Anne‐Claude Gingras, Jean‐François Couture, Eric I. Campos

This study investigates how BLBS-causing H3.3 mutations affect H3K36 methylation and effector protein binding, revealing molecular similarities across mutations.

bioRxiv · Sep 9, 2025 · PreprintMolecular Biology

Development of a multifunctional toolkit of intrabody-based biosensors recognizing the V5 peptide tag: highlighting applications with G protein-coupled receptors

Manel Zeghal, Kevin Matte, Angelica Venes, Shivani Patel, Geneviève Laroche, Sabina Sarvan, Monika Joshi, Jean‐François Couture, Patrick M. Giguère

The paper develops a toolkit of intrabody-based biosensors recognizing the V5 peptide tag and applies them to study G protein-coupled receptor signaling.

bioRxiv · Feb 5, 2023 · PreprintMolecular Biology