Author

Christine Fagotto‐Kaufmann

Centre National de la Recherche ScientifiqueORCID 0009-0004-9892-5243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

François FagottoiD· 2 shared A. Cousido-SiahiD· 1 shared Alastair G. McEweniD· 1 shared ALBERTO D. PODJARNYiD· 1 shared Anna BonhoureiD· 1 shared Anne DebantiD· 1 shared Arpoudamarie Roc· 1 shared Artur RuppeliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

François FagottoORCID

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3 papers

Recent·Most cited

Structural analysis of HERC2/UBE3A and HERC2/DOCK10 complexes provides new insights into the molecular basis of Angelman, Angelman-like and Dup15q Syndromes

Auguste Demenge, JiaWen Lim, Arpoudamarie Roc, Boglárka Zámbó, Gergő Gógl, A. Cousido-Siah, Alastair G. McEwen, Anna Bonhoure, Camille Kostmann, Christine Fagotto‐Kaufmann, Pascal Eberling, Judit Ősz, ALBERTO D. PODJARNY, Eduardo Howard, Christelle Golzio, , Gilles Travé

The paper analyzes the structural and functional interactions of HERC2/UBE3A and HERC2/DOCK10 complexes to understand their role in Angelman and Dup15q Syndromes.

Nature Communications · Oct 31, 2026Peer-reviewedBiochemistry

A microfluidic approach to explore mesoderm tissue dynamics and its natural variability

Guillaume Desgarceaux, Majid Layachi, Christine Fagotto‐Kaufmann, Laura Casanellas, François Fagotto

This study uses a microfluidic system to investigate mesoderm tissue dynamics and variability in Xenopus embryos, showing that tissue mechanics are governed by cell stiffness and mechanical coupling.

bioRxiv · Apr 24, 2026 · PreprintDevelopmental Biology

Dynamic remodelling of cadherin contacts in embryonic mesenchymal cells during differential cell migration

David Rozema, Christine Fagotto‐Kaufmann, Artur Ruppel, Paul F. Lasko, François Fagotto

The paper investigates how cadherin contacts are dynamically remodeled during differential cell migration in Xenopus mesoderm, revealing mechanisms of contact disruption and their relationship with cortical tension.

Developmental Cell · Jul 3, 2025Peer-reviewedDevelopmental Biology