Author

Paul F. Lasko

McGill UniversityORCID 0000-0002-4037-3501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:Drosophila· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Greco HernándeziD· 2 shared Hong Ryul HaniD· 2 shared Andrea Hildebrandt· 1 shared Anke BuschiD· 1 shared Annabelle DoldiD· 1 shared Artur RuppeliD· 1 shared Brook L. FalkiD· 1 shared Christine Fagotto‐KaufmanniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersDevelopmental Biology

Greco HernándezORCID

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4 papers

Recent·Most cited

Dynamic remodelling of cadherin contacts in embryonic mesenchymal cells during differential cell migration

David Rozema, Christine Fagotto‐Kaufmann, Artur Ruppel, Paul F. Lasko, François Fagotto

The paper investigates how cadherin contacts are dynamically remodeled during differential cell migration in Xenopus mesoderm, revealing mechanisms of contact disruption and their relationship with cortical tension.

Developmental Cell · Jul 3, 2025Peer-reviewedDevelopmental Biology

Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in Drosophila melanogaster

Lisa Shao, Jaclyn M. Fingerhut, Brook L. Falk, Hong Ryul Han, Giovanna Maldonado, Yuemeng Qiao, Vincent Lee, Elizabeth Hall, Liang Chen, Gordon Polevoy, Greco Hernández, Paul F. Lasko, Julie A. Brill

This study shows that eIF4E-5 is essential for spermatid cyst polarization, individualization, and male fertility in Drosophila by regulating caspase activity and Soti localization.

Development · Jan 25, 2023Peer-reviewedDevelopmental Biology

Makorin1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation

Annabelle Dold, Hong Ryul Han, Niankun Liu, Andrea Hildebrandt, Mirko Brüggemann, Cornelia Rücklé, Heike Hänel, Anke Busch, Petra Beli, Kathi Zarnack, Julian König, Jean‐Yves Roignant, Paul F. Lasko

This study shows that Makorin1 promotes oskar translation by displacing Bruno from its 3' UTR, essential for embryonic patterning and germ cell formation in Drosophila.

PLoS Genetics · Jan 24, 2020Peer-reviewedDevelopmental Biology

Drosophila ribosomal protein S5b is essential for oogenesis and interacts with distinct RNAs

Jian Kong, Ho Jae Han, Julie Bergalet, Louis Philip Benoit Bouvrette, Greco Hernández, Nam-Sung Moon, Hojatollah Vali, Éric Lécuyer, Paul F. Lasko

This study shows that RpS5b is essential for oogenesis in Drosophila and interacts with mRNAs related to mitochondrial function.

bioRxiv · Apr 6, 2019 · PreprintDevelopmental Biology