Author

Maria Savchenko

ORCID 0009-0005-0577-1458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:batch correction / integration· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexander BagaeviD· 2 shared A. SarachakoviD· 1 shared Aleksandr Zaitsev· 1 shared Alexander A. NesmeloviD· 1 shared Alexander Kuznetsov· 1 shared Alexandr Zaitsev· 1 shared Anastasia Zolotar· 1 shared Anastasia ZotovaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Alexander BagaevORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 17, 2026

✦ In-depth digest

Benchmarking of bulk transcriptomic harmonization tools in a multi-platform B-cell lymphoma cohort identifies feature-specific quantile normalization and surrogate variable analysis as top-performing methods

Daniil M. Nikitin, Nikolay Borisov, Maria Savchenko…·Arsen Arakelyan

Across 7,174 multi-platform lymphoma transcriptomes, only surrogate variable analysis and feature-specific quantile normalization corrected batch effects while keeping subtype and normal B-cell differences; top-scoring MNN erased biomarker correlations.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintApr 30, 2026

AI-based separation of malignant cell- and microenvironment-specific gene expression from bulk RNA sequencing enhances biomarker interpretation

Anastasia Zolotar, Daniil S. Wiebe, Arman Petrosyants…·Alexander Bagaev

Helenus separates malignant and microenvironment gene expression from bulk RNA-seq to improve biomarker interpretation in cancer.

DOI 10.64898/2026.04.28.721082

humanbulk RNA-seq

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