Author

Alexander Kuznetsov

University of Freiburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. SarachakoviD· 1 shared Akanksha AnandiD· 1 shared Aleksandr Zaitsev· 1 shared Alexander BagaeviD· 1 shared Amira MetwalyiD· 1 shared Anastasia Zolotar· 1 shared Anastasia ZotovaiD· 1 shared Andrea Proaño-VascoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. SarachakovORCID

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2 papers

Recent·Most cited

AI-based separation of malignant cell- and microenvironment-specific gene expression from bulk RNA sequencing enhances biomarker interpretation

Anastasia Zolotar, Daniil S. Wiebe, Arman Petrosyants, Boris Shpak, Natalia Khotkina, Valentina Beliaeva, Ekaterina Ivleva, Linda Balabanian, Maksim Chelushkin, Daniiar Dyikanov, Maria Savchenko, Sheila T. Yong, Danil Litvinov, Anastasia Zotova, Alexander Kuznetsov, , Alexander Bagaev

Helenus separates malignant and microenvironment gene expression from bulk RNA-seq to improve biomarker interpretation in cancer.

bioRxiv · Apr 30, 2026 · PreprintCancer Biology

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibition

Theresa Baumeister, Andrea Proaño-Vasco, Amira Metwaly, Karin Kleigrewe, Alexander Kuznetsov, Linus R. Schömig, Martin Borgmann, Mohammed Khiat, Akanksha Anand, Julia Strangmann, Katrin Böttcher, Dirk Haller, Andreas Dunkel, Veronika Somoza, Sinah Reiter, , Michael Quante

This study shows that high-fat diets promote GEAC by altering the microbiota-Bile Acid axis and inhibiting FXR, with FXR agonists like OCA slowing disease progression.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2025Peer-reviewedCancer Biology