Y Yamauchi

This study measures cyclin-CDK dissociation constants in living cells using FCCS with optimized fluorescent proteins, revealing insights into cyclin-CDK binding redundancy.

The paper uses a topology-based theory to predict and validate independent control of G2-M and G1-S checkpoints in fission yeast cell cycle by analyzing CDK-cyclin complex dynamics.

The paper develops an algorithm to identify buffering structures in chemical reaction networks by leveraging an inverse theorem of the law of localization, enabling efficient detection of modular regulatory units.