GeneticsEpigeneticsPeer-reviewed
Preimplantation Embryos Amplify Stress-Induced Changes in Sperm-Derived miRNA Content to Mediate Transgenerational Epigenetic Inheritance
Alexandre Champroux, Yang Tang, David A. Dickson…·Larry A. Feig
This study shows that chronic stress in male mice reduces sperm miR-34c levels through astrocyte-derived exosomes, leading to transgenerational anxiety and reduced sociability in offspring.
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