Stefanie Böhm

The paper reports an extended structure of the human nuclear pore complex, revealing TREX-2 components as integral parts of the nuclear ring.

This study uses cryo-electron tomography to show vault particles associate with ER and nuclear envelope membranes and enclose ribosomes in Dictyostelium discoideum.

The paper develops a computational method to measure membrane thickness in cryo-electron tomograms, revealing systematic variations across organelles and supporting hydrophobic matching models.

This study shows that nuclear pore complexes dilate during cell differentiation and that Nup133 deficiency prevents this dilation, leading to nuclear envelope instability.

This study shows that Hrq1/RECQL4 regulates DNA intrastrand crosslink repair and its misregulation contributes to genomic instability in cancer.