Hans‐Georg Kräusslich

The paper reports an extended structure of the human nuclear pore complex, revealing TREX-2 components as integral parts of the nuclear ring.

This study shows Lenacapavir causes HIV-1 capsid damage, exposing genomic DNA in nuclear speckles and altering capsid structure.

This study identifies SP2 as a trigger for HIV-1 MA lattice maturation, showing it binds MA to induce structural changes and enhance viral infectivity.

This study investigates how HIV-1 capsids pass through nuclear pores, finding that capsids retain their structure and cause NPC scaffold rings to crack.

This study shows that nuclear pore complexes dilate during cell differentiation and that Nup133 deficiency prevents this dilation, leading to nuclear envelope instability.

This paper describes an engineered nanobody that modulates GFP binding with small molecules, enabling controlled study of GFP fusion proteins in biological processes.

This study benchmarks tomographic acquisition schemes for cryo electron tomography to optimize resolution for subtomogram averaging using HIV-1 lattice.

The paper shows clathrin-mediated endocytosis transitions from flat to curved structures when 70% of clathrin is assembled, driven by changes in clathrin-adaptor ratio and membrane tension.