BioengineeringbioRxivPreprint
Structure-Guided Discovery of High-Affinity Methotrexate Aptamers for Electrochemical Drug Monitoring
Micaela Sequeira, Thiago Coimbra Pimenta, Rafael Vieira…·Elena Eremeeva
This paper develops two high-affinity MTX-binding DNA aptamers using structure-guided methods and validates their use in electrochemical drug monitoring.
DOI 10.64898/2026.10.06.757117