Lee Min Leong

The paper uses ArcLight to image voltage dynamics in mitral/tufted glomeruli of anesthetized mice, revealing odor-evoked excitatory and suppressive signals and concentration-specific responses.

The paper identifies a non-monotonic concentration-response relationship in mitral/tufted cells of the mouse olfactory bulb, suggesting interglomerular inhibition facilitates odor discrimination.

This paper shows how modifying the electrostatic environment of a fluorescent protein's beta-barrel can control chromophore fluorescence properties and response kinetics.

The paper shows that recent odor experiences selectively modulate olfactory sensitivity in specific glomeruli of the mouse olfactory bulb for up to 30 seconds.

This study shows that S1 hydrophobic residues in voltage sensing phosphatase (VSP) modulate voltage sensing and enzymatic activity by altering voltage dependence and kinetics.

The paper develops a novel GEVI that brightens upon depolarization by manipulating threonine sidechains to control chromophore conformation and fluorescence transitions.

The paper develops a new family of GEVIs using intermolecular FRET, showing larger voltage-dependent signals and improved cell type specificity.