Author

Nancy J. Zeleznik‐Le

Loyola University ChicagoORCID 0009-0005-2432-9892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Emmalee R. AdelmaniD· 2 shared John Hackett BushwelleriD· 2 shared Nicholas J. Achille· 2 shared Adam M. BoultoniD· 1 shared Akihiko YokoyamaiD· 1 shared Ashish KabraiD· 1 shared Benjamin I. LeachiD· 1 shared Charles S. HemenwayiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Emmalee R. AdelmanORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 10, 2026

The chromatin reader protein MLLT1 is critical to maintain normal B lymphopoiesis

Janani Prakash, Nicholas J. Achille, Emmalee R. Adelman…·Nancy J. Zeleznik‐Le

This study shows that MLLT1 is essential for normal B lymphopoiesis, as its deletion in mice leads to reduced B cell development and altered gene expression.

DOI 10.64898/2026.08.08.743534

mouseexperimental assay

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BiochemistrybioRxivPreprintSep 1, 2025

The MLLT3 YEATS domain is a dual reader of histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking epigenetic and RNA signaling to regulate hematopoiesis

Adam M. Boulton, Ashish Kabra, Nicholas J. Achille…·John Hackett Bushweller

This study shows the MLLT3 YEATS domain binds both histone marks and the 7SK RNA, influencing hematopoietic lineage commitment and gene expression.

DOI 10.1101/2025.09.01.673558

humanChIP-seq

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