Author

Tiago Rito

The Francis Crick InstituteORCID 0009-0005-2497-9457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

James BriscoeiD· 3 shared Ashley R.G. LibbyiD· 2 shared Arthur RadleyiD· 1 shared Guillaume CharrasiD· 1 shared Jake Cornwall-ScoonesiD· 1 shared Juliet CheniD· 1 shared Madeleine DemuthiD· 1 shared Marie‐Charlotte DomartiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersDevelopmental Biology

James BriscoeORCID

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3 papers

Recent·Most cited

Systems BiologyDevelopmentPeer-reviewedJun 15, 2026

Boundary constraints can determine pattern emergence

Yi Ting Loo, Juliet Chen, Ryan Harrison…·Timothy E. Saunders

The paper shows that boundary constraints influence the spatial patterning of cell fates during development through a reaction-diffusion model and Wnt signaling.

3 citations

humanstatistical model

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedJan 13, 2025

An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast

Ashley R.G. Libby, Tiago Rito, Arthur Radley, James Briscoe

The paper uses an in vivo CRISPR screen in chick embryos to identify MLLT3 as a regulator of neural fate specification from the caudal epiblast.

4 citations

experimental assayperturbation response prediction

𝕏 PostBluesky

Developmental BiologyNaturePeer-reviewedDec 18, 2024

Notochord and axial progenitor generation by timely BMP and NODAL inhibition during vertebrate trunk formation

Tiago Rito, Ashley R.G. Libby, Madeleine Demuth…·James Briscoe

The paper uses single-cell transcriptomics to study vertebrate trunk formation, identifying signaling pathways that regulate notochord and tissue development in human pluripotent stem cells.

58 citationstop 2%

scRNA-seqstatistical model

𝕏 PostBluesky