Ashley R.G. Libby

The paper uses an in vivo CRISPR screen in chick embryos to identify MLLT3 as a regulator of neural fate specification from the caudal epiblast.

The paper uses single-cell transcriptomics to study vertebrate trunk formation, identifying signaling pathways that regulate notochord and tissue development in human pluripotent stem cells.

This study shows that TBXT dose affects the timing of EMT in human gastruloids without compromising mesoderm differentiation.

This study uses caudalized human pluripotent stem cell organoids to model neural tube axial elongation, showing gene expression patterns and morphological features similar to development.

This study shows that reducing E-cadherin in 3D encapsulated human pluripotent stem cells leads to extraembryonic fates and multilineage differentiation, mimicking early embryonic development.