Author

Huijie Yuan

University of DundeeORCID 0009-0005-3149-7050Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Andrew T. FerenbachiD· 3 shared Daan M. F. van AalteniD· 3 shared Alfonso Manuel D’AlessioiD· 1 shared Andrii GorelikiD· 1 shared Conor W. MitchelliD· 1 shared Florence Authier· 1 shared Jan Skov PederseniD· 1 shared Kristian LytjeiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Andrew T. FerenbachORCID

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3 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedOct 3, 2025

Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms

Sara Basse Hansen, Sergio G. Bartual, Huijie Yuan…·Daan M. F. van Aalten

This study presents multi-domain OGA structures from Trichoplax adhaerens and human, revealing allosteric regulatory mechanisms involving the pHAT domain.

5 citations

humannon-human primate

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Molecular BiologybioRxivPreprintJul 12, 2025

A triple fluorescence approach to measure O-GlcNAc dyshomeostasis in stem cells

Huijie Yuan, Andrew T. Ferenbach, Daan M. F. van Aalten

This paper introduces a triple fluorescence stem cell sorting approach to measure O-GlcNAc dyshomeostasis and demonstrates its utility for high-throughput screening.

2 citations

mouseexperimental assay

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Cell BiologyOpen BiologyPeer-reviewedJan 1, 2025

O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control

Conor W. Mitchell, Huijie Yuan, Marie Sønderstrup-Jensen…·Daan M. F. van Aalten

The paper identifies O-GlcNAcylation of DDX3X as a regulator of the G1/S-phase transition and shows its role in cell cycle control and neurogenesis in OGT-CDG.

4 citations

mouseproteomics

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