Author

Sergio G. Bartual

Aarhus UniversityORCID 0000-0002-9755-8152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Andrew T. FerenbachiD· 2 shared Daan M. F. van AalteniD· 2 shared Alex N. BullockiD· 1 shared Allan BayatiD· 1 shared Andrii GorelikiD· 1 shared Christina FengeriD· 1 shared Huijie YuaniD· 1 shared Ignacy CzajewskiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Andrew T. FerenbachORCID

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Author profile →

3 papers

Recent·Most cited

Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms

Sara Basse Hansen, Sergio G. Bartual, Huijie Yuan, Olawale G. Raimi, Andrii Gorelik, Andrew T. Ferenbach, Kristian Lytje, Jan Skov Pedersen, Taner Drace, Thomas P. Boesen, Daan M. F. van Aalten

This study presents multi-domain OGA structures from Trichoplax adhaerens and human, revealing allosteric regulatory mechanisms involving the pHAT domain.

Nature Communications · Oct 3, 2025Peer-reviewedMolecular Biology

Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly

R.J. Adamson, N. Connor Payne, Sergio G. Bartual, Ralph Mazitschek, Alex N. Bullock

The paper determines the crystal structure of the KEAP1-CUL3 complex and develops a TR-FRET assay to study its binding, showing CDDO reduces affinity without disrupting the interaction.

Free Radical Biology and Medicine · May 6, 2023Peer-reviewedMolecular Biology

An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal

Michaela Omelková, Christina Fenger, Marta Murray, Trine Bjørg Hammer, Veronica M. Pravatà, Sergio G. Bartual, Ignacy Czajewski, Allan Bayat, Andrew T. Ferenbach, Marios P. Stavridis, Daan M. F. van Aalten

The paper shows that an OGT variant causes reduced pluripotent stem cell self-renewal and lower stem cell marker levels in mouse embryonic stem cells.

bioRxiv · Mar 13, 2023 · PreprintMolecular Biology