Author

Samantha G. Fernandez

Harvard UniversityORCID 0009-0005-3303-9619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Philip J. KranzuschiD· 3 shared Sonomi YamaguchiiD· 2 shared Aaron G. SchmidtiD· 1 shared Anne A. RoffleriD· 1 shared Arielle WoznicaiD· 1 shared Bianca Tiwari· 1 shared Collin McNairy· 1 shared Douglas R. WassarmaniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

Philip J. KranzuschORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 12, 2026

Human interferon stimulated genes target ancient features of animal and bacterial viral replication

Samantha G. Fernandez, Jill E. Hutchinson, Joel MJ Tan…·Philip J. Kranzusch

The paper shows human ISGs can restrict bacterial phage replication, revealing conserved antiviral mechanisms across kingdoms.

3 citations

bacteria (other)human

𝕏 PostBluesky

MicrobiologyNaturePeer-reviewedFeb 18, 2026

Activating and inhibiting nucleotide signals coordinate bacterial anti-phage defense

Sonomi Yamaguchi, Samantha G. Fernandez, Douglas R. Wassarman…·Philip J. Kranzusch

This study identifies a bacterial anti-phage defense system, Clover, which uses nucleotide signals to dynamically regulate antiviral immunity while avoiding cellular toxicity.

6 citationstop 1%

bacteria (other)experimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 4, 2025

A choanoflagellate cGLR-STING pathway reveals evolutionary links between bacterial and animal immunity

Yao Li, Hunter C. Toyoda, Samantha G. Fernandez…·Philip J. Kranzusch

The paper identifies a cGLR-STING signaling pathway in choanoflagellates, showing evolutionary links between bacterial and animal immunity.

1 citation

non-human primateproteomics

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 16, 2023

Ribosome rescue factor PELOTA modulates translation start site choice and protein isoform levels of transcription factor C/EBPα

Samantha G. Fernandez, Lucas Ferguson, Nicholas T. Ingolia

This study identifies PELOTA's role in modulating C/EBPα isoform selection through ribosome rescue and mTOR-mediated effects during myeloid cell development.

1 citation

humanproteomics

𝕏 PostBluesky