Narendra Kumar Gonepudi

This study uses single-molecule imaging to show peptide inhibitors bind to prefusion viral fusion proteins with varying stoichiometry and rapid kinetics, challenging the canonical prehairpin-intermediate model.

This study characterizes a bacteriophage, Curly, against Klebsiella pneumoniae, showing its efficacy in reducing bacterial burden and inflammation in human cells and a mouse model.

This study uses single-molecule FRET to show that gp41-directed antibodies stabilize or open the prefusion-closed state of HIV-1 Env, revealing two neutralization mechanisms.