Author

Yufan He

The University of Texas at Tyler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Junyu Liu· 2 shared Maolin LuiD· 2 shared Narendra Kumar GonepudiiD· 2 shared Priyamvada AcharyaiD· 2 shared Revansiddha H. KatteiD· 2 shared Wang XuiD· 2 shared Yang HaniD· 2 shared Baoshan ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

Junyu Liu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FLASH X-rays preserve neutrophil chromatin to boost antitumor immunity

Xiaolin Shi, Si Qiu, Yiwei Yang, YongChao Jiang, Jianxin Wang, Xiaofeng Ding, Yufan He, Meiqi Lv, Hongyan Li, Qing Li, Baosheng Li, Zheng Zhou, Kui Zhou, Dexin Xiao, Peng Li, , Haowen Zhang

This study shows FLASH X-rays preserve neutrophil chromatin, reducing NET formation and enhancing antitumor immunity when combined with anti-PD-1 therapy.

bioRxiv · Oct 13, 2026 · PreprintCancer Biology

Peptide inhibitors recognize prefusion viral fusion proteins with heterogeneous stoichiometry and rapid kinetics

Revansiddha H. Katte, Junyu Liu, Yufan He, Bhishem Thakur, Xiao Huang, Jared J. Lindenberger, Wang Xu, Narendra Kumar Gonepudi, Yang Han, Katarzyna Janowska, Robert J. Edwards, Priyamvada Acharya, Maolin Lu

This study uses single-molecule imaging to show peptide inhibitors bind to prefusion viral fusion proteins with varying stoichiometry and rapid kinetics, challenging the canonical prehairpin-intermediate model.

bioRxiv · Sep 15, 2026 · PreprintMicrobiology

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

Wang Xu, Narendra Kumar Gonepudi, Junyu Liu, Yufan He, Revansiddha H. Katte, Ran Wang, Harry Baffour Awuah, Yang Han, Baoshan Zhang, Jian Yu, Bo Hu, David D Ho, Priyamvada Acharya, Peter D. Kwong, Maolin Lu

This study uses single-molecule FRET to show that gp41-directed antibodies stabilize or open the prefusion-closed state of HIV-1 Env, revealing two neutralization mechanisms.

bioRxiv · Aug 12, 2026Microbiology