Developmental BiologybioRxivPreprint
TBX3 is essential to establish the posterior boundary of anterior genes and up-regulate posterior genes with HAND2 during onset of limb bud development
Geoffrey Soussi, Aušra Girdžiušaitė, Shalu Jhanwar…·Aimée Zúñiga
The paper identifies TBX3 as a key transcription factor for establishing the antero-posterior axis polarity in mouse limb buds by repressing anterior genes and up-regulating posterior genes with HAND2.
DOI 10.1101/2024.01.30.577998