Author

Brandon Chacón

University of California, San FranciscoORCID 0000-0002-4776-5946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Licia SelleriiD· 2 shared Marta LosaiD· 2 shared Aimée ZúñigaiD· 1 shared Angela MorabitoiD· 1 shared Aragorn JonesiD· 1 shared Aušra GirdžiušaitėiD· 1 shared Axel ViseliD· 1 shared Diane E. DickeliD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Licia SelleriORCID

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2 papers

Recent·Most cited

Cell Cycle Arrest of a "Zippering" Epithelial Cell Cluster Shapes the Face and is Disrupted in Craniofacial Disorders

T. Qu, Brandon Chacón, L. Faure, Marta Losa, Rocío Hernández-Martínez, Kelsey R. Robinson, Aragorn Jones, Steven Lisgo, J. De Anda, M. Risolino, Georgia Panagiotakos, Elizabeth J. Leslie, Igor I. Adameyko, Licia Selleri

The paper identifies a novel epithelial population, Zippering Lambda, whose cell cycle arrest is critical for facial prominence fusion and is disrupted in orofacial clefting.

bioRxiv · Jul 28, 2025 · PreprintDevelopmental Biology

A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2

Marta Losa, Iros Barozzi, Marco Osterwalder, Viviana E. Hermosilla, Angela Morabito, Brandon Chacón, Peyman Zarrineh, Aušra Girdžiušaitė, Jean Denis Benazet, Jianjian Zhu, Susan Mackem, Terence Dante Capellini, Diane E. Dickel, Nicoletta Bobola, Aimée Zúñiga, , Licia Selleri

The paper reconstructs a gene regulatory network directed by PBX1/2 and HAND2 in mouse limb development, showing their genetic interaction and tissue-specific function.

Nature Communications · Jul 6, 2023Peer-reviewedDevelopmental Biology