Author

Maxwell J. Hedayati

Allen Institute for Cell ScienceORCID 0009-0005-4041-080XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Amber PhaniD· 2 shared Brock RobertsiD· 2 shared Caroline HookwayiD· 2 shared Chamari S. WijesooriyaiD· 2 shared Chantelle L. LeveilleiD· 2 shared Clare Ruth GamliniD· 2 shared Emmanuel E. Sanchez· 2 shared Erik A. EhlersiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Amber PhanORCID

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Author profile →

2 papers

Recent·Most cited

Dynamics of ML-based Morphological Features Indicate a Shear Stress-Dependent Bifurcation of hiPSC-Derived Endothelial Cell States

Erin Angelini, Chantelle L. Leveille, Serge E. Parent, Rebecca J. Zaunbrecher, Tiffany Barszczewski, Julie C. Dixon, Fatwir S. Mohammed, Benjamin Morris, Jessica S. Yu, Joy Arakaki, Renske J. Dupar, Jacqueline H. Edmonds, Erik A. Ehlers, Clare Ruth Gamlin, Maxwell J. Hedayati, , Matheus Palhares Viana

The paper uses ML to analyze morphological dynamics of hiPSC-derived endothelial cells under shear stress, identifying a bifurcation between two stable cell states.

bioRxiv · Jul 11, 2026 · PreprintBiophysics

A human induced pluripotent stem (hiPS) cell model for the holistic study of epithelial to mesenchymal transitions (EMTs)

Caroline Hookway, Antoine Borensztejn, Leigh K. Harris, Tiffany Barszczewski, Sara G. Carlson, Gökhan Dalgin, Suraj Mishra, Ellen M. Adams, Julie C. Dixon, Renske J. Dupar, Jacqueline H. Edmonds, Erik A. Ehlers, Alexandra J. Ferrante, Margaret A. Fuqua, Clare Ruth Gamlin, , Susanne M. Rafelski

The paper presents a hiPS cell model to study EMTs by comparing 2D and 3D cultures, measuring changes in cell function, markers, organization, and environment.

Nature Methods · Jun 15, 2026Peer-reviewedCell Biology