Author

James A. Rouse

Cold Spring Harbor LaboratoryORCID 0009-0005-4262-2363Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander S. Harris· 1 shared Alexey S. RevenkoiD· 1 shared Arianna Anderson· 1 shared Brian OhiD· 1 shared Christopher R. VakociD· 1 shared Corina AmoriD· 1 shared David L. SpectoriD· 1 shared Disha AggarwaliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alexander S. Harris

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 28, 2026

CAR T cell targeting of inflammatory myeloid progenitors in the bone marrow remodels border-associated macrophages and reverses cognitive aging

Alexander S. Harris, James A. Rouse, 郭广冉…·Corina Amor

This study shows that targeting inflammatory myeloid progenitors in the bone marrow with CAR T cells reduces neuroinflammation and cognitive decline in aging and Alzheimer's models.

DOI 10.64898/2026.09.27.754777

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 27, 2026

Patient-derived organoid xenografts reveal the multifaceted role of the lncRNA MALAT1 in breast cancer progression

Disha Aggarwal, Suzanne Russo, Kendall L. Anderson…·David L. Spector

This study evaluates MALAT1-targeting ASOs in breast cancer using patient-derived organoid models, showing MALAT1's role in alternative splicing, metastasis, and tumor-stroma interactions.

DOI 10.64898/2026.04.02.716096

humanorganoid / primary culture

𝕏 PostBluesky