Emelia Karlsson

This study uses molecular dynamics and electrophysiology to uncover the mechanism of pH sensing in the bacterial ion channel sTeLIC, identifying key Glu residues involved in alkaline gating.

This study investigates how psychostimulant derivatives modulate the prokaryotic pentameric ligand-gated ion channel sTeLIC through a vestibular pocket, revealing a structure-function mechanism for allosteric potentiation.