Emma J. van Grinsven

Structure of the mammalian ciliary transition zone microtubule doublet

The paper reports the structure of the mammalian ciliary transition zone microtubule doublet using cryo-electron tomography, revealing unique proteins and their roles in microtubule stabilization and transport regulation.

Microtubule organization and molecular architecture of ciliary basal bodies in multiciliated airway cells

The paper uses expansion microscopy to map the 3D microtubule organization in human airway multiciliated cells, revealing the role of NEDD1 in basal foot-dependent microtubule organization.

Rab27-dependent egress of SARS-CoV-2 via secretory amphisomes

This study uses expansion microscopy to show SARS-CoV-2 exits cells via Rab27-dependent amphisome fusion, identifying a potential therapeutic target.

Immortalization of human nasal and bronchial airway epithelial cells for genome editing applications

The paper describes the immortalization of human nasal and bronchial airway epithelial cells using hTERT overexpression, enabling long-term genome editing studies.

SSNA1 organizes the distal luminal centriolar network and promotes ciliogenesis without microtubule association

This study identifies SSNA1 as a centriolar protein in the distal lumen that promotes ciliogenesis without microtubule association, challenging previous views of its function.