Joshua M. Pratt

This study demonstrates growing macroscopic functional human tissues on 3D-printed peptide hydrogels, enabling centimeter-scale neural organoids and directional axonal communication.

This study shows that human astrocytes have distinct metabolic profiles compared to non-human primate astrocytes, which influence neuronal development timing and trajectories.

This study shows that APOE4 impairs lipoprotein secretion in microglia, leading to lysosomal and mitochondrial dysfunction and a proinflammatory phenotype.

This study identifies CK2 as a key driver of glial inflammation in neurodegenerative disorders and shows that its inhibition reduces inflammation in AD models.