Cynthia Laflamme

This study shows that neutrophil Fc gamma RI expression determines oxidative responses in human blood, with increased ROS production linked to Fc gamma RI levels in both healthy individuals and lupus patients.

This study shows that the multivalent prefusion SARS-CoV-2 Spike protein does not directly activate human neutrophils ex vivo, even in the presence of anti-S antibodies.

This study identifies a prototypical neutrophil phenotype in lupus patients, showing reduced viability, altered surface markers, and responsiveness to immune complexes, suggesting Fcγ receptor engagement as a key driver.