Author

Liam McDonnell

Queensland University of TechnologyORCID 0009-0006-1572-8549Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Bingyin PengiD· 3 shared Claudia Estelle VickersiD· 3 shared Samuel Evans· 3 shared Zeyu Mike LuiD· 3 shared Carlos H. Luna‐FloresiD· 2 shared Chengqiang WangiD· 2 shared Colin Stephen ScottiD· 2 shared Robert E. SpeightiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersSynthetic Biology

Bingyin PengORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintOct 9, 2026

Evolutionary stabilisation of stressful metabolism via integrated biocomputing and essential-gene metabolic locking circuits

Zeyu Mike Lu, Craig P. Barry, Masahiro Tominaga…·Bingyin Peng

The paper develops synthetic genetic circuits in yeast to stabilize metabolic stress from terpene production, showing that coupling essential genes to synthetic pathways improves strain stability.

DOI 10.64898/2026.09.01.748751

yeastbulk RNA-seq

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 26, 2024

Cyanamide-inducible expression of homing nuclease I-SceI for iterative genome engineering and parallel promoter characterisation in Saccharomyces cerevisiae

Liam McDonnell, Samuel Evans, Zeyu Mike Lu…·Bingyin Peng

The paper develops a cyanamide-inducible system for genome engineering in yeast, enabling selectable marker recycling and promoter characterization.

1 citation

yeastexperimental assay

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Synthetic BiologybioRxivPreprintJan 30, 2024

The integration of tandem gene repeats via a bacterial type-II toxin-antitoxin-mediated gene amplification (ToxAmp) system and stability visualisation in Saccharomyces cerevisiae

Samuel Evans, Zeyu Mike Lu, Liam McDonnell…·Bingyin Peng

The paper develops a bacterial toxin-antitoxin system to manipulate and visualize tandem gene repeat copy numbers in yeast.

DOI 10.1101/2024.01.30.578080

yeastexperimental assay

𝕏 PostBluesky