Zeyu Mike Lu

The paper develops synthetic genetic circuits in yeast to stabilize metabolic stress from terpene production, showing that coupling essential genes to synthetic pathways improves strain stability.

The paper develops a cyanamide-inducible system for genome engineering in yeast, enabling selectable marker recycling and promoter characterization.

The paper develops a bacterial toxin-antitoxin system to manipulate and visualize tandem gene repeat copy numbers in yeast.

This study shows that fusing terpene synthases increases metabolic flux by boosting enzyme stability and expression, leading to higher nerolidol production.

This paper demonstrates that synthetic in vivo compartmentalisation of enzymes in yeast significantly increases product titre and modulates product ratios.

This paper introduces IBM, a method that systematically splits proteins into logic gates using inteins, enabling inducible control of protein function.

This paper shows anthrax toxin can target and modulate pain by acting on nociceptive neurons through ANTXR2, with potential for new pain therapeutics.