Author

Ziwei Zhou

Chinese Academy of SciencesORCID 0009-0006-2554-5703Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Eric XuiD· 2 shared Wanchao YiniD· 2 shared Chunhao Zhu· 1 shared Erli You· 1 shared Fulai ZhouiD· 1 shared Gengfu XiaoiD· 1 shared Hualiang JiangiD· 1 shared Jian ZhangiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

H. Eric XuORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 27, 2026

Fine-tuning an intracellular allosteric pocket programs GPCR signaling bias

Xinchao Shi, Ruidi Zhu, Kewei CHANG…·Jian Zhang

This study fine-tunes an intracellular allosteric pocket of NTSR1 to program GPCR signaling bias, revealing how ligand modifications alter transducer coupling and downstream signaling.

DOI 10.64898/2026.10.22.760766

mouseproteomics

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Molecular BiologybioRxivPreprintOct 6, 2020

Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19

Wanchao Yin, Xiaodong Luan, Zhihai Li…·H. Eric Xu

The paper discovers suramin as a potent inhibitor of SARS-CoV-2 RNA polymerase and provides its structural mechanism for repurposing in treating COVID-19.

5 citations

experimental assaydrug response / drug discovery

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